USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O00264 USC-OGP 2-DE database:  O00264 O00264 General information about the entry View entry in simple text format Entry name PGRC1_HUMAN Primary accession number O00264 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Membrane-associated progesterone receptor component 1; Short=mPR;. Gene name Name=PGRMC1 Synonyms=HPR6.6, PGRMC Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0205: pI=4.57; Mw=23744 Cross-references UniProtKB/Swiss-Prot O00264; PGRC1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PGRC1_HUMAN Primary accession number O00264 Secondary accession number(s) B7Z1L3 Q9UGJ9 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 161) Name and origin of the protein Description RecName: Full=Membrane-associated progesterone receptor component 1; Short=mPR; Gene name Name=PGRMC1 Synonyms=HPR6.6, PGRMC Encoded on Name=PGRMC1; Synonyms=HPR6.6, PGRMC Keywords 3D-structure; Alternative splicing; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Lipid-binding; Membrane; Microsome; Phosphoprotein; Receptor; Reference proteome; Steroid-binding; Transmembrane; Transmembrane helix. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Y12711; CAA73248.1; -; mRNA EMBL AK293618; BAH11549.1; -; mRNA EMBL AC004835; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471161; EAW89881.1; -; Genomic_DNA EMBL BC034238; AAH34238.1; -; mRNA EMBL AJ249131; CAB65109.1; -; Genomic_DNA CCDS CCDS14576.1; -. [O00264-1]; . CCDS CCDS65313.1; -. [O00264-2]; . RefSeq NP_001269550.1; NM_001282621.1. [O00264-2]; . RefSeq NP_006658.1; NM_006667.4. [O00264-1]; . UniGene Hs.90061; -; . PDB 4X8Y; X-ray; 1.95 A; A/B=72-195 PDBsum 4X8Y; -; . ProteinModelPortal O00264; -; . SMR O00264; -; . BioGrid 116068; 43; . IntAct O00264; 54; . MINT MINT-2997519; -; . STRING 9606.ENSP00000217971; -; . DrugBank DB00514; Dextromethorphan; . DrugBank DB00540; Nortriptyline; . iPTMnet O00264; -; . PhosphoSitePlus O00264; -; . SwissPalm O00264; -; . OGP O00264; -; . EPD O00264; -; . PaxDb O00264; -; . PeptideAtlas O00264; -; . PRIDE O00264; -; . TopDownProteomics O00264-1; -. [O00264-1]; . DNASU 10857; -; . Ensembl ENST00000217971; ENSP00000217971; ENSG00000101856. [O00264-1]; . Ensembl ENST00000535419; ENSP00000442821; ENSG00000101856. [O00264-2]; . GeneID 10857; -; . KEGG hsa:10857; -; . UCSC uc011mts.4; human. [O00264-1]; . CTD 10857; -; . DisGeNET 10857; -; . GeneCards PGRMC1; -; . HGNC HGNC:16090; PGRMC1; . HPA HPA002877; -; . MIM 300435; gene; . neXtProt NX_O00264; -; . OpenTargets ENSG00000101856; -; . PharmGKB PA33248; -; . eggNOG KOG1110; Eukaryota; . eggNOG ENOG4111UG0; LUCA; . GeneTree ENSGT00730000110959; -; . HOGENOM HOG000187840; -; . HOVERGEN HBG059971; -; . InParanoid O00264; -; . KO K17278; -; . OMA AYDKEIG; -; . OrthoDB EOG091G0PXT; -; . PhylomeDB O00264; -; . TreeFam TF314562; -; . Reactome R-HSA-6798695; Neutrophil degranulation; . ChiTaRS PGRMC1; human; . GeneWiki PGRMC1; -; . GenomeRNAi 10857; -; . PRO PR:O00264; -; . Proteomes UP000005640; Chromosome X; . Bgee ENSG00000101856; -; . CleanEx HS_PGRMC1; -; . ExpressionAtlas O00264; baseline and differential; . Genevisible O00264; HS; . GO GO:0012505; C:endomembrane system; IBA:GO_Central; . GO GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0035579; C:specific granule membrane; TAS:Reactome; . GO GO:0020037; F:heme binding; IBA:GO_Central; . GO GO:0005496; F:steroid binding; TAS:ProtInc; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . Gene3D 3.10.120.10; -; 1; . InterPro IPR001199; Cyt_B5-like_heme/steroid-bd; . Pfam PF00173; Cyt-b5; 1; . SMART SM01117; Cyt-b5; 1; . SUPFAM SSF55856; SSF55856; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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